For research purposes only

Cat. No BA94673161

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Description of biological activity

Glutamine-Fructose-6-Phosphate Amidotransferase (GFAT) inhibitor. In an assay using COS cells transfected with GFAT-alpha or GFAT-beta [WO2005/40150 A2, 2005] the compound showed IC50 8 μmol/l for GFAT-alpha and 3.25 μmol/l for GFAT-beta.

TECHNICAL INFORMATION

1-(4-methoxy-naphthalene-1-carbonyl)-6,7-dimethoxy-isoquinoline-4-carboxylic acid Glutamine-Fructose-6-Phosphate Amidotransferase (GFAT) inhibitor.

IUPAC Name: 1-(4-methoxy-naphthalene-1-carbonyl)-6,7-dimethoxy-isoquinoline-4-carboxylic acid

CAS Number: 851331-58-3

Purity: > 96% chemical purity (LCMS)

1H-NMR spectrum (click to enlarge)

REFERENCES

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