For research purposes only

Cat. No BA121016532

Availability - 10 mg in stock
- larger amount can be synthesized in 8 weeks

Description of biological activity

Factor Xa and Thrombin inhibior. The compound inhibits human Factor Xa with Ki 0.08 nmol/l and human Thrombin with Ki 3100 nmol/l [Bioorg. Med. Chem. Lett. 2010, 20, 1373-1377], it showed pronounced anticoagulant activity [Bioorg. Med. Chem. Lett. 2009, 19, 2179-2185].

Keywords: Anticoagulant

TECHNICAL INFORMATION

1-(4-methoxy-phenyl)-7-oxo-6-[4-(2-oxo-piperidin-1-yl)-phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid amide Factor Xa and Thrombin inhibior.

IUPAC Name: 1-(4-methoxy-phenyl)-7-oxo-6-[4-(2-oxo-piperidin-1-yl)-phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid amide

CAS Number: 503612-47-3

Purity: > 96% chemical purity (LCMS)

1H-NMR spectrum (click to enlarge)

REFERENCES

1. J. Med. Chem., 2007,В 50, 5339 - 5356

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